Scrub typhus: Clinical spectrum and outcome

Clinical Manifestations & Complications of Scrub Typhus

Introduction Scrub typhus, also known as tsutsugamushi disease, is an acute febrile illness caused by infection with Orientia tsutsugamushi and characterized by focal or disseminated vasculitis and perivasculitis, which may involve the lungs, heart, liver, spleen, and central nervous system (1,2,3).The symptoms are usually mild and the clinical course selflimited, with spontaneous recovery afte...

Scrub-typhus.

Scrub typhus is an important emerging tropical infection that can have severe manifestations in children leading to intensive care admission. It is caused by Orientia tsutsugamushi, a gram negative bacterium transmitted to humans by the bite of larval trombiculid mites. The organism is endemic in south-east Asia and the disease is reported from virtually all parts of India. The hallmark of this...

Clinical and paraclinical profile, and predictors of outcome in 90 cases of scrub typhus, Meghalaya, India

BACKGROUND India is an integral component of "tsutsugamushi triangle" which depicts a part of the globe endemic to scrub typhus. Owing to frequent outbreaks witnessed in different parts of the country in the recent past, scrub typhus is described as a re-emerging infectious disease in India. The present study aimed to study the clinical and paraclinical profile, complications and predictors of ...

Risk factors leading to fatal outcome in scrub typhus patients.

Scrub typhus is a potentially fatal infectious disease. However, to this date, no epidemiologic study on mortality of complicated scrub typhus has been reported. We reviewed the clinical records of 302 patients with diagnosis of scrub typhus who were admitted to our institute between January 2000 and December 2006. In total, 297 patients with scrub typhus were analyzed and the mortality rate of...

Scrub typhus complicating pregnancy.